A five-mile (8km) territory of a Mississippi River nearby St Louis, Missouri, has been sealed to vessels as rising H2O levels caused “hazardous conditions”, a US Coast Guard said.
Storms and tornadoes have lashed a segment in new days, flourishing rivers and causing peep flooding.
Missouri Governor Jay Nixon pronounced 13 people in a state had died in a floods.
He pronounced a National Guard had been called in to assistance internal authorities.
Aerial footage showed H2O from a Mississippi River engulfing buildings in a evacuated city of West Alton, north of St Louis, on Tuesday.
In a city of Union, about 50 miles (80km) west of St Louis, buildings were partly submerged by serious flooding from a Missouri, Meramec and Bourbeuse rivers.
Coast Guard orator Capt Martin Malloy pronounced a high H2O levels and quick currents had led them to tighten a territory of a Mississippi nearby St Louis – a bustling track for blurb shipping.
River levels are foresee to rise on Thursday and Mr Nixon warned that a conditions could get worse before it gets better.
He pronounced a National Guard would yield confidence in evacuated areas and approach trade divided from sealed roads.
“These citizen soldiers will yield much-needed support to state and internal initial responders, many of whom have spent a final several days operative around a time responding to record rainfall and flooding,” he pronounced in a statement.
Nr Nixon combined that 3 new flood-related deaths had been detected on Tuesday, lifting a genocide fee in a state given a storms began over a weekend to 13.
Many of a victims have been trapped in vehicles swept off flooded roads.
South-west of St Louis, a territory of Interstate 44 was sealed by flooding nearby a city of Rolla while partial of Interstate 70 was also sealed in a beside state of Illinois.
Many other smaller roads were also sealed opposite a dual states, where inundate warnings were in effect.
Floods also flooded a wastewater diagnosis plant south of St Louis on Monday, causing sewage to upsurge directly into rivers and streams.
The flooding in Missouri and southern Illinois began over a weekend after as most as 10ins (25cm) of sleet fell in some areas in a matter of hours.
It came after serious storms over a Christmas holiday claimed during slightest 49 lives opposite southern and western states of a US.
Parts of eastern Oklahoma, Arkansas and Illinois are still theme to inundate warnings.