West Ham winger Michail Antonio has cold from a England patrol since of a hamstring injury.
The uncapped 26-year-old reported a damage after Saturday’s 3-2 Premier League better by Leicester City.
Antonio was means to finish a 90 mins during London Stadium, though West Ham manager Slaven Bilic indicated thereafter that he was a doubt.
England face Germany in a accessible on Wednesday before hosting Lithuania in a World Cup qualifier on Sunday.
Antonio’s deficiency serve weakens a aggressive options of England trainer Gareth Southgate.
Forwards Harry Kane, Daniel Sturridge, Danny Welbeck and Wayne Rooney are all out by injury, while Theo Walcott was left out of a squad.
In further to Antonio, West Ham mislaid centre-back Winston Reid to a leg injury, while midfielder Pedro Obiang was taken off on a bracket after rolling his ankle.
On a injuries to Antonio and Reid, Bilic said: “Hopefully, they will be fit after a general break.”